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Peutz-Jeghers Syndrome - JMI ArticlesArticles in our collection about Peutz-Jeghers Syndrome published during the 1960sTitle: POLYPOSIS OF THE SMALL INTESTINE, WITH PIGMENTATION OF THE FACE, BUCCAL MUCOSA, AND DIGITS Authors: J. OLDFIELD Journal: BRITISH JOURNAL OF SURGERY Date: Abstract: SINCE THE INITIAL DESCRIPTION BY DEUTZ IN 1934 AND THE REVIEW BY JEGHERS AND HIS ASSOCIATES IN 1949THIS INTERESTING SYNDROME HAS BEEN RECOGNIZED AND REPORTED WITH INCREASING FREQUENCY. RICHTERICHVAN-BAERLE (1956) REVIEWS A TOTAL OF 47 CASES UP TO 1955 WHICH WERE PROVEN BY OPERATION, AUTOPSY, OR BIOPSY. Link: Click here to read this article Title: A CASE OF PEUTZ-JEGHER SYNDROME Authors: R. KUMAR Journal: BRITISH JOURNAL OF SURGERY Date: Abstract: THE PRESENCE OF BLACK PIGMENTED SPOTS OF NON-ADDISONIAN ORIGIN ON THE LIPS AND BUCCAL MUCOSA WAS REPORTED IN TWINS BY SIR J. HUTCHINSON IN 1896. ONE OF THESE TWINS DIED 21 YEARS LATER FROM AN INTUSSUSCEPTION, PROBABLY DUE-TO AN INTESTINAL POLYP. THE FIRST PROVED CASE OF MULTIPLE INTESTINAL POLYPS, WITH MELANIN SPOTS ON LIPS, DIGITS, AND BUCCAL MUCOSA, WAS PUBLISHED BY PEUTZ IN 1921. Link: Click here to read this article Title: THE PEUTZ-JEGHERS SYNDROME [ABRIDGED] Authors: D. B. E. FOSTER Journal: PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE Date: 1960 Abstract: THE PEUTZ-JEGHERS SYNDROME CONSISTS OF FAMILIAL POLYPOSIS OF THE GASTRO-INTESTINAL TRACT, ASSOCIATED WITH PIGMENTATION OF THE BUCCAL MUCOSA, THE FACE AND OTHER PARTS OF THE SKIN. THIS CONDITION, ONCE SEEN, CAN BE DIAGNOSED BY SIMPLE OBSERVATION. IT HAS ONLY BEEN GENERALLY RECOGNIZED FOR THE PAST EIGHT TO TEN YEARS, THOUGH BY 1957 BARTHOLOMEW ET AL. WERE ABLE TO RECORD 75 CASES OF THE SYNDROME. Link: Click here to read this article Title: INTESTINAL POLYPS AND PEUTZ-JEGHER'S SYNDROME Authors: Journal: JAMA Date: 1960 Abstract: THE SYNDROME OF SMALL INTESTINAL POLYPOSIS ASSOCIATE & WITH MELANIN, SPOTS OF THE ORAL MUCOSA, LIPS, AND DIGITS HAS RARELY BEEN SURGICALLY TREATED. INASMUCH AS THE AREA OF POLYP FORMATION IS NOT LOCALIZED, SURGICAL RESECTION OF ALL INVOLVED SEGMENTS OF BOWEL IS IMPOSSIBLE. Link: Click here to read this article Title: FAMILIAL INTESTINAL POLYPOSIS WITH MELANOSIS ORIS: THE SYNDROME OF PEUTZ AND JEGHERS REPORT OF A CASE Authors: BERNARD S. MOSKOW, CHARLES TENEN Journal: REPRINTED FROM ORAL SURGERY, ORAL MEDICINE AND ORAL PATHOLOGY Date: 1960 Abstract: WHEN ATTENTION IS DIRECTED TO WHAT, IN A SENSE, IS A "MEDICAL CURIOSITY," THERE OFTEN IS A TENDENCY FOR THE RARITY SUDDENLY TO BECOME SOMEWHAT MORE COMMON. THIS IS PRECISELY WHAT HAS OCCURRED IN THE LAST TEN YEARS WITH RESPECT TO A RATHER UNUSUAL GROUP OF SYMPTOMS KNOWN AS THE PEUTZ-JEGHERS SYNDROME. Link: Click here to read this article Title: DUODENAL POLYPOSIS ASSOCIATED WITH MUCOCUTANEOUS MELANOSIS (PEUTZ-JEGHERS SYNDROME) Authors: ARTHUR S. TUCKER, ROBERT P. BOLANDE Journal: JOURNAL OF DISEASES OF CHILDREN Date: 1960 Abstract: INTESTINAL POLYPS ARE RELATIVELY COMMON IN CHILDREN, BUT THOSE WHICH OCCUR IN CONJUNCTION WITH MELANOTIC PIGMENTATION AT THE MUCOCUTANEOUS JUNCTIONS ARE SEEN MUCH LESS FREQUENTLY. PEDIATRICIANS WHO EXAMINE CHILDREN WITH INTESTINAL BLEEDING AND FIND SMALL FOCI OF DARK PIGMENT ON THE LIPS AND ADJACENT CUTANEOUS AND MUCOSAL SURFACES SHOULD BE ALERT TO THE POSSIBILITY OF THE PRESENCE OF INTESTINAL POLYPS AS REPORTED BY PEUTZ, IN 1921, AND BY JEGHERS, IN 1944. Link: Click here to read this article Title: THE PEUTZ-JEGHERS SYNDROME: GASTROINTESTINAL POLYPOSIS WITH MUCOCUTANEOUS MELANIN PIGMENTATION. Authors: NORMAN SHRIFTER Journal: ABSTRACTS OF CURRENT LITERATURE Date: 1961 Abstract: TURELL, R., KREEL, I., SELEY, G. P. SURG. CLIN. NORTH AM., 39: 1309 (OCT.) 1959. BECAUSE OF THE APPARENT EXTREME RARITY OR ABSENCE OF A CANCER POTENTIAL IN THE POLYPS OF PATIENTS WITH PEUTZ-JEGHERS SYNDROME, CONSERVATIVE THERAPY IS JUSTIFIED. Link: Click here to read this article Title: PEUTZ-JEGHERS SYNDROME Authors: B. KNUTSEN Journal: JAMA Date: 1961 Abstract: T NORSKE LAEGEFOREN-VOL. 81:831 (JULY 1) 1961. OF TWIN BOYS, AGED 4 1/2 YEARS, ONE HAD A COMPLETE PEUTZ-JEGHERS SYNDROME WITH INTESTINAL POLYPOSIS AND CHARACTERISTIC PIGMENTATION OF THE LIPS; THE OTHER HAD ONLY PIGMENTATION. Link: Click here to read this article Title: PEUTZ-JEGHER SYNDROME: A CASE REPORT Authors: A. R. COOKE Journal: MEDICAL JOURNAL OF AUSTRALIA Date: 1961 Abstract: THE SYNDROME OF MUCO-CUTANEOUS PIGMENTATION AND INTESTINAL POLYPOSIS, NOW CALLED PEUTZ-JEGHERS SYNDROME, WAS FIRST DESCRIBED BY SIR JONATHAN HUTCHISON IN 1896. HE DESCRIBED PECULIAR PIGMENTATION ABOUT THE LIPS AND BUCCAL MUCOSA IN IDENTICAL TWIN GIRLS, ONE OF WHOM SUBSEQUENTLY DIED OF INTUSSUSCEPTION AT THE AGE OF 21 YEARS. PEUTZ IN 1921 FIRST RECOGNIZED THE POLYPOSIS AND PIGMENTATION AS A SYNDROME. Link: Click here to read this article Title: PEUTZ-JEGHERS SYNDROME: A FURTHER FAMILY HISTORY Authors: G. KEEN, M. A. MURRAY Journal: BRITISH MEDICAL JOURNAL Date: 1962 Abstract: THE ASSOCIATION OF SMALL-INTESTINAL POLYPOSIS AND BUCCAL PIGMENTATION, OFTEN PRESENTING AS A FAMILIAL CONDITION, HAS AROUSED GREAT INTEREST IN RECENT YEARS. IN 1896 JONATHAN HUTCHINSON DESCRIBED TWIN GIRLS WHO BAD A PECULIAR SPOTTY, PIGMENTATION AROUND THIR MOUTHS. Link: Click here to read this article Title: INTESTINAL POLYPOSIS, ASSOCIATED WITH MUCOCUTANEOUS PIGMENTATION Authors: LLOYD G. BARTHOLOMEW, CLARENCE E. MOORE, DAVID C. DAHLIN Journal: REPRINTED FROM SURGERY, GYNECOLOGY AND OBSTETRICS Date: 1962 Abstract: SINCE 1921, WHEN PEUTZ REPORTED HIS FIRST OBSERVATIONS "ABOUT A NOTEWORTHY CASE OF FAMILIAL POLYPOSIS OF THE INTESTINAL MUCOUS MEMBRANE AND THOSE OF THE NASOPHARYNX ACCOMPANIED BY PECULIAR PIGMENTATIONS OF THE SKIN AND MUCOUS MEMBRANE," 174 CASES HAVE BEEN REPORTED IN THE LITERATURE. MOST OF THESE REPORTS HAVE NECESSARILY DEALT WITH AN INDIVIDUAL CASE OR AT MOST A SMALL SERIES OF CASES. Link: Click here to read this article Title: INTESTINAL POLYPOSIS WITH MUCOCUTANEOUS PIGMENTATION: THE PEUTZ-JEGHERS SYNDROME Authors: J. STEPHEN DOYLE, M. J. RYAN, ANTHONY P. CLERY Journal: IRISH JOURNAL OF MEDICAL SCIENCE Date: 1962 Abstract: THE PEUTZ-JEGHERS SYNDROME IS AN UNUSUAL FAMILIAL DEFECT IN WHICH POLYPS OCCUR IN THE STOMACH AND INTESTINES TOGETHER WITH A, MACULAR MELANOTIC PIGMENTATION OF THE SKIN AND CERTAIN MUCOUS MEMBRANES. THE POLYPS ARE HAMARTOMAS, NOT TRUE NEOPLASMS. THE COLOUR OF THE PIGMENTATION VARIES FROM LIGHT BROWN TO BLUISH BLACK. Link: Click here to read this article Title: THE SPECTRUM OF THE PEUTZ-JEGHERS SYNDROME: REPORT OF 3 CASES Authors: RICHARD G. FARMER, WILLIAM A. HAWK, RUPERT B. TURNBULL JR. Journal: REPRINTED FROM AMERICAN JOURNAL OF DIGESTIVE DISEASES Date: 1963 Abstract: THE SYNDROME OF MUCOCUTANEOUS PIGMENTATION AND INTESTINAL POLYPOSIS-DESCRIBED BY PEUTZ IN 1921 AND AMPLIFIED BY JEGHERS, MCKUSICK, AND KATZ IN 1949-HAS RECEIVED CONSIDERABLE ATTENTION IN THE LAST DECADE. THE IMPORTANCE OF RECOGNIZING THE PEUTZ-JEGHERS SYNDROME AND OF DIFFERENTIATING IT FROM OTHER FORMS OF GASTROINTESTINAL POLYPOSIS HAS BEEN EMPHASIZED. THE SIGNIFICANCE OF THE DIFFERENCE LIES MAINLY IN THE MALIGNANT POTENTIAL OF THE VARIOUS POLYPOSIS SYNDROMES. Link: Click here to read this article Title: PEUTZ-JEGHERS SYNDROME: A CLINICAL-PATHOLOGICAL STUDY OF A LARGE FAMILY WITH A 10-YEAR FOLLOW-UP Authors: DANIEL BURDICK, JOHN T. PRIOR, GERARD T. SCANLON Journal: REPRINTED FROM CANCER Date: 1963 Abstract: IN 1921, PEUTZ FIRST DESCRIBED AN UNUSUAL SYNDROME OF FAMILIAL GASTROINTESTINAL POLYPOSIS ASSOCIATED WITH PIGMENTATION OF THE SKIN AND MUCOUS MEMBRANES. HOWEVER, THIS CONDITION WAS SELDOM RECOGNIZED UNTIL JEGHERS ET AL. REPORTED COMPREHENSIVELY ON 10 CASES IN 1949. FOLLOWING THIS, THE CONDITION BECAME KNOWN AS THE PEUTZ-JEGHERS SYNDROME, AND IT HAS BEEN REPORTED WITH INCREASING FREQUENCY. Link: Click here to read this article Title: PEUTZ-JEGHERS SYNDROME Authors: JACQUES A. LOEB Journal: REPRINTED FROM CANADIAN JOURNAL OF SURGERY Date: 1963 Abstract: JACQUES A LOEB IN 1921 PEUTZ REPORTED "A VERY REMARKABLE CASE OF FAMILIAL POLYPOSIS OF MUCOUS MEMBRANE OF INTESTINAL TRACT AND NASOPHARYNX ACCOMPANIED BY PECULIAR PIGMENTATION OF THE SKIN AND MUCOUS MEMBRANE". FOLLOWING THIS PUBLICATION A SMALL NUMBER OF CASES WAS REPORTED BUT IT WAS NOT UNTIL 1949, WHEN JEGHERS, MCKUSICK AND KATZ AGAIN DREW ATTENTION TO THE CONDITION, THAT THE TERM "PEUTZ-JEGHERS SYNDROME" WAS COINED. Link: Click here to read this article Title: PEUTZ-JEGHERS SYNDROME Authors: JOHN C. BELISARIO Journal: MEDICAL JOURNAL OF AUSTRALIA Date: 1964 Abstract: I AM WRITING TO ASK IF YOU WILL BE GOOD ENOUGH TO CORRECT AN ERROR I MADE IN YOUR JOURNAL ON FEBRUARY 16, 1963, PAGE 256. I STATED AT THAT TIME THAT THE TITLE "PEUTZ-JEGHERS SYNDROME" SHOULD BE CHANGED TO THE "PEUTZ-TOURAINE SYNDROME", OR AT LEAST THE "PEUTZ-TOURAINE-JEGHERS SYNDROME". Link: Click here to read this article Title: ORAL PIGMENTATION AND INTESTINAL POLYPOSIS (PEUTZ-JEGHERS SYNDROME) Authors: A. W. DICKIE Journal: ULSTER MEDICAL JOURNAL Date: 1964 Abstract: IN 1921 PEUTZ DESCRIBED A FAMILY WITH INTESTINAL POLYPOSIS AND SPOTS OF MELANIN PIGMENTATION IN AND AROUND THE MOUTH. PRIOR TO THIS, IN 1896, SIR JONATHAN HUTCHINSON DESCRIBED TWO GIRLS WITH PIGMENTED PATCHES IN THE ORAL MUCOSA AND AROUND THE MOUTH. LATER PARKES WEBER (1919) REPORTED THAT ONE OF THESE TWINS DIED OF WHAT APPEARED TO BE AN INTUSSUSCEPTION. Link: Click here to read this article Title: Peutz-Jeghers syndrome Authors: el Hefnawi H;Rasheed A; Journal: J Egypt Med Assoc Date: 1966 Abstract: Link: Click here to read this article Title: Peutz-Jeghers' syndrome Authors: Norvell ST; Journal: N S Med Bull Date: 1966 Sep Abstract: Link: Click here to read this article Title: Peutz-Jeghers syndrome: satisfactory survival with 30 inches of small intestine Authors: Gibbons WD; Journal: Med J Aust Date: 1967 Apr 29 Abstract: Link: Click here to read this article Title: Seventeen patients with Peutz-Jehgers syndrome in four generations Authors: McAllister AJ;Hicken NF;Latimer RG;Condon VR; Journal: Am J Surg Date: 1967 Dec Abstract: Link: Click here to read this article Title: Seventeen patients with Peutz-Jehgers syndrome in four generations Authors: McAllister AJ;Hicken NF;Latimer RG;Condon VR; Journal: Am J Surg Date: 1967 Dec Abstract: Link: Click here to read this article Title: Peutz-Jeghers syndrome with report of a case Authors: Bell RP; Journal: Va Med Mon (1918 ) Date: 1967 Feb Abstract: Link: Click here to read this article Title: Peutz-Jeghers syndrome: sporadic and familial Authors: Neely MG;Gillespie G; Journal: Br J Surg Date: 1967 May Abstract: Link: Click here to read this article Title: A case of Peutz-Jeghers syndrome, simulating hyperemesis gravidarum Authors: Evans AR; Journal: Proc R Soc Med Date: 1969 Apr Abstract: Link: Click here to read this article Title: Peutz-Jeghers syndrome with metastases to an abdominal incision Authors: Mackman S;Perna G;Gossett F; Journal: Arch Surg Date: 1969 Jan Abstract: Link: Click here to read this article Title: Familial polyposis of the entire gastrointestinal tract Authors: Yonemoto RH;Slayback JB;Byron RL;Rosen RB; Journal: Arch Surg Date: 1969 Oct Abstract: Link: Click here to read this article
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Jeghers Medical Index, St. Elizabeth Health Center, 1044 Belmont Ave., Youngstown, OH 44501
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